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Figure 2 | Frontiers in Zoology

Figure 2

From: Lifetime development of behavioural phenotype in the house mouse (Mus musculus)

Figure 2

Enhanced spatial memory in offspring of mothers with physical activity during pregnancy. Transgenic (tg) and wild type (wt) mice modelling Alzheimer's disease were tested for spatial memory in a Barnes maze. The mothers of half of the animals were physically active by using a running wheel (RW) during pregnancy while the other mothers lived in standard housing (SH) conditions without access to a running wheel. None of the mice tested as adults at an age of 136 days had access to a running wheel themselves. Offspring of running mothers performed significantly better in the test, indicating a long lasting effect of environmental conditions during pregnancy on cognitive behaviour in adult offspring. Figure redrawn after [103].

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