Figure 2From: Lifetime development of behavioural phenotype in the house mouse (Mus musculus)Enhanced spatial memory in offspring of mothers with physical activity during pregnancy. Transgenic (tg) and wild type (wt) mice modelling Alzheimer's disease were tested for spatial memory in a Barnes maze. The mothers of half of the animals were physically active by using a running wheel (RW) during pregnancy while the other mothers lived in standard housing (SH) conditions without access to a running wheel. None of the mice tested as adults at an age of 136 days had access to a running wheel themselves. Offspring of running mothers performed significantly better in the test, indicating a long lasting effect of environmental conditions during pregnancy on cognitive behaviour in adult offspring. Figure redrawn after [103].Back to article page