Figure 1

Alignment of chelicerate Proboscipedia, Deformed, Sex comb reduced, Ultrabithorax sequences. Aligned is a fragment covering the hexapeptide (core in red) and homeodomain (blue) plus some flanking sequences. The deduced proteins sequences are from the chelicerates Cupiennius salei (Cs; American wandering spider), Achaearanea tepidariorum (At; common house spider), Archegozetes longisetosus (Al; mite), Endeis spinosa (Es; seaspider) the fruit fly Drosophila melanogaster (Dm; insect), the centipedes Pachymerium ferrugineum (Pf; myriapod), Strigamia maritima (Sm; myriapod), and the isopod Porcellio scaber (Ps; crustacean). Amino acids identical to the upper sequence are indicated as dashed "-"; dots "." are used to indicate gaps that have been introduced for alignment purposes. The linker between hexapeptide and homeodomain in the Es-pb sequence is rather long, therefore 19aa are not shown (marked as //19aa// in the alignment). Please note, some of the At, Al and Pf sequences from the GenBank still contain ambiguous sites that result in an unknown amino acid in the deduced protein sequence; these are indicated as "X" in the alignment. Accession numbers of the sequences used: Cs: AM419029, CAA07498, AM419032, AM419030, AM419031, CAA07500, CAA07501; At: AF151997, AF151995, AF151996, AF151998; Al: AF071406, AF071403, AF071407; Es: ABD46724. ABD46727, ABD46728; Dm: CAA45272, NP_477201, NP_524248, NP_536752; Pf: CAB75743, CAB75746; Sm: ABD16212, Ps: BAE97002.