Table 6 Individual searches for our transcriptome datasets (no background color) and the JGI genomes of a sponge (pink), a mollusk (violet), and an annelid (green)

Petrosia ficiformis

578

247

680

346

234

510

157

Crella elegans

472

247

247

307

85

300

147

Amphimedon queenslandica

1667/614

539

1320

413/370/279

290

656

454

Cephalotrix hogkongiensis

272/173/103

139

-

137

343/309/110

205

168/89

Cerebratulus marginatus

286/495

101

131

140

358/109/167

271

233

Chiton olivaceus

498

358

-

123

289/174/96

168

65

Octopus vulgaris

916

217

-

-

324/247

445

101

Lottia gigantea

2404

724

1245

350

231

549

230

Sipunculus nudus

451/232/241

-

-

-

-

-

-

Hormogaster samnitica

464/546/684/456

521/268/260/388/314/170

-

200/197

350/314/238/173/133/108

521/482

171/952

Capitella teleta

2580/2612/2673/2985

785

1204

207

307/199/141

459/445

610

Metasiro americanus

600

780

552

340

58/179/ 344

493

-

Alipes grandidieri

196/203

151

115/416

66/82

80/294

273

415

TGF-β

TGF-β1

Activin

Smad 1

Smad 2

Smad 3

dpp

BMP1

BMP3

BMP5

BMP6

Petrosia ficiformis

435

-

230

-

186

-

184

-

-

102

Crella elegans

90

-

408

98

190

-

150

-

-

140

Amphimedon queenslandica

371

-

408/412/181

-

-

-

1035

-

-

413

Cephalotrix hogkongiensis

251

118

151

-

307

-

208

-

114

-

Cerebratulus marginatus

413

120

473

-

266

-

172

-

114

-

Chiton olivaceus

109

285

77

-

242

181

110

-

152

Octopus vulgaris

-

500

302

-

-

97

107

308

-

679

Lottia gigantea

516

523/576

466

428

-

406

332

381

104

-

Sipunculus nudus

-

59

-

-

-

-

153

-

-

-

Hormogaster samnitica

446/317

192

472

-

417

104

226

96

-

-

Capitella teleta

511

471/429

309

452

339

1

239

-

-

Metasiro americanus

362/374

407/71

-

287

-

351

340/613

117

411

160

Alipes grandidieri

425/507

-

117

-

94

173

113

480

-

-

Hedgehog

Housekeeping genes

Hedgehog/ Hedgling

Patched

Smoothened/ Frizzled

Ci/Gli

TPI

ATPB

MAT

PFK

FBA

EF-1α

CAT

Petrosia ficiformis

1212

-

288/252/133

343

165

180

94

239

231

253

383/422

Crella elegans

327

-

165/156

517

218

267

377/162

139

172/128

460

374

Amphimedon queenslandica

1184

-

300/289/275

143

228

184

439/385

840

359

249

508/498

Cephalotrix hogkongiensis

-

-

199

-

141

264

-

698

-

191/79

152

Cerebratulus marginatus

-

-

100

248

393

100

705

38

331

255

Chiton olivaceus

303

-

465

105

235

499

247

421

121

-

190

Octopus vulgaris

-

145

590/305/221

-

79

509

332

815

60

109

335

Lottia gigantea

355

527

879/572/489

1493

252

521

410

770

273

469

510

Sipunculus nudus

91

-

-

-

222

325

247

-

243/113

333

509

Hormogaster samnitica

386/301/127

555/536/107

838

695

150

178

402/106

585

213

230/133

458

Capitella teleta

329

1465

589/597/591

235

240

479

393

826

364

463

534

Metasiro americanus

236

670

75/577

597

236

210

261/182

766

213

207

101

Alipes grandidieri

285

132

66

681

235

289

107/78

525

202

124

431